Statistical publications

More Publications

Software

A considerable amount of software grew out of my research. Most of this code is made available as packages for the freely available software R and can be downloaded from CRAN.

bpp

Kaspar Rufibach, Paul Jordan, Markus Abt (2016): bpp: Computations Around Bayesian Predictive Power

SurvRegCensCov

Stanislas Hubeaux and Kaspar Rufibach (2014): SurvRegCensCov: Weibull Regression for a Right-Censored Endpoint with Interval-Censored Covariate

logconcens

Dominic Schuhmacher, Kaspar Rufibach, and Lutz Duembgen (2011): logconcens: Maximum likelihood estimation of a log-concave density based on censored data

logcondiscr

Kaspar Rufibach, Fadoua Balabdaoui, Hanna Jankowski, and Kathrin Weyermann (2011): logcondiscr: Estimate a Log-Concave Probability Mass Function from Discrete i.i.d. Observations

biostatUZH

Leonhard Held and Kaspar Rufibach, with further contributions by others (2010): biostatUZH: Misc Tools of the Department of Biostatistics, EBPI, University of Zurich

selectMeta

Kaspar Rufibach (2010): selectMeta: Estimation of Weight Functions in Meta Analysis

OrdFacReg

Kaspar Rufibach (2009): OrdFacReg: Least Squares, Logistic, and Cox-Regression with Ordered Predictors

OrdMonReg

Fadoua Balabdaoui, Kaspar Rufibach, Filippo Santambrogio (2009): OrdMonReg: Compute least squares estimates of one bounded or two ordered isotonic regression curves

reporttools

Rufibach, K (2008): reporttools: Generate LaTeX Tables of Descriptive Statistics

modehunt

Kaspar Rufibach and Guenther Walther (2007): modehunt: Multiscale Analysis for Density Functions

smoothtail

Kaspar Rufibach and Samuel Mueller (2006): smoothtail: Smooth Estimation of GPD Shape Parameter

logcondens

Kaspar Rufibach and Lutz Duembgen (2006): Estimate a Log-Concave Probability Density from i.i.d. Observations

Teaching and thesis supervision

I am regularly teaching to statisticians and non-statisticians about various biostatistical topics. Slides are available for download for some of the courses.

At Roche, I am responsible for the technical training planning of about 200 biostatistics staff. I coordinate a major chunk of the biostatistics courses for non-statistics functions. A full-day introductory biostatistics course that I have given together with Marcel Wolbers has been selected as part of the official training program for all Roche affiliates globally.

2019/07: Advanced methods for group-sequential trials

Kaspar Rufibach and Marcel Wolbers, pre-conference course at ISCB 40, Leuven

2019/03: Advanced methods for group-sequential trials

Kaspar Rufibach and Marcel Wolbers, Roche-internal course

2019/01: Introduction to statistics in clinical trials

Kaspar Rufibach, Roche-internal course

2018/03: Group-sequential and adaptive clinical trial designs, with R practicals

Marc Vandemeulebroecke, Kaspar Rufibach, Daniel Sabanes-Bove, and Marcel Wolbers, course on behalf of the BBS

2018: Optimism-corrected treatment effect estimates in subgroups displayed in forest plots for time-to-event outcomes

Ke Li, master thesis to obtain MSc in biostatistics, Department of Biostatistics, University of Zurich

2017/11: Introduction to statistics.

Kaspar Rufibach, Roche-internal course

2017/07: Sample size planning and survival analysis in clinical trials.

Kaspar Rufibach and Marcel Wolbers, Roche-internal course

2017/04: Introduction to statistics.

Kaspar Rufibach, Roche-internal course

2017/03: Introduction to statistics.

Kaspar Rufibach, Roche-internal course

2016/11: Introduction to statistics.

Kaspar Rufibach, Roche-internal course

2016/10: Introduction to statistics.

Kaspar Rufibach, Roche-internal course

2016/08: Introduction to statistics.

Kaspar Rufibach, Roche-internal course

2016/05: Introduction to statistics.

Kaspar Rufibach, Roche-internal course

2016/03-11: Specific biostatistical topics in clinical trials.

Kaspar Rufibach, courses for medical doctors at five hospitals

2016/02: Introduction to statistics in clinical trials.

Kaspar Rufibach, Roche-internal course

2016/01-02: Introduction to statistics.

Kaspar Rufibach, Certificate of Advanced Studies (CAS) course, as part of the Master of Advanced Studies in Managed Health Care

2016: Joint Modelling of Overall Survival and Progression Free Survival

Matthias Meller, master thesis to obtain MSc in biostatistics, University of Ulm

2015/11: Introduction to statistics.

Kaspar Rufibach, Roche-internal course

2015/10: Introduction to statistics.

Kaspar Rufibach, Roche-internal course

2015/05: Introduction to statistics.

Kaspar Rufibach, Roche-internal course

2015/01: Introduction to statistics.

Kaspar Rufibach, Certificate of Advanced Studies (CAS) course, as part of the Master of Advanced Studies in Managed Health Care

2014/06-11: Four workshops on specific biostatistical topics in clinical trials.

Kaspar Rufibach, courses for medical doctors at four hospitals

2014/01-03: Introduction to statistics.

Kaspar Rufibach, Certificate of Advanced Studies (CAS) course, as part of the Master of Advanced Studies in Managed Health Care

2014: Estimation from Interval-censored Time-to-event Data: Method Comparison by Simulation based on GALLIUM Study for Follicular Lymphoma

Monika Hebeisen, thesis to obtain MSc in biostatistics, Department of Biostatistics, University of Zurich

2013/11: Group-sequential designs

Kaspar Rufibach, within MSc biostatistics program at University of Zurich

2013/06: Analysis of longitudinal data

Kaspar Rufibach, full-day course for Roche biostatisticians

2013: Analysis of time-to-event data with interval- or left-censored covariates

Stanislas Hubeaux, 6-month full-time internship within Department of Biostatistics, Roche Basel

2013/11: Workshop on survival analysis in oncology.

Kaspar Rufibach, Roche-internal course

2013/06-2014/04: Survival analysis in oncology.

Kaspar Rufibach, courses for medical doctors at seven hospitals

2013: What does a PSA bounce look like? A numerical and graphical description of the prostate-specific antigen (PSA) bounce phenomenon in patients treated for prostate cancer with brachytherapy only

Philipp Boutellier, master thesis to obtain MSc in medicine, University of Zurich

2012/11: Statistical Methods in Clinical Research

Kaspar Rufibach, within MSc biostatistics program at University of Zurich

2012/01-03: Introduction to statistics.

Kaspar Rufibach, Certificate of Advanced Studies (CAS) course, as part of the Master of Advanced Studies in Managed Health Care

2012: Inter- and Intrareader variability of Ratingen score in the Swiss Clinical Quality Management database

Dominik Loiero, master thesis to obtain MSc in medicine, University of Zurich

2011/09-11: Statistical Methods in Clinical Research

Kaspar Rufibach and Eva Furrer, within MSc biostatistics program at University of Zurich

2011/09: Statistics in oncology.

Kaspar Rufibach, cancer biology PhD program, University of Zurich

2011/04: How to write a scientific paper -- statistical aspects.

Kaspar Rufibach, course for medical students, Zurich University hospital

2011/01: Analysis of longitudinal data

Leonhard Held and Kaspar Rufibach, University of Mainz, Germany

2011/02: Introduction to biostatistics.

Kaspar Rufibach, continuing education for radiologists, Bern University Hospital

2011: Determinants of TNFa inhibitor prescription in the Swiss Clinical Quality Management cohort of axial Spondylarthropathy patients

Almut Scherer, Semester thesis, Department of Biostatistics, University of Zurich

2010/06: Analysis of longitudinal data

Leonhard Held and Kaspar Rufibach, MSc of Medical Biometry program, University of Heidelberg

2010/02-06: Analysis of longitudinal data

Leonhard Held and Kaspar Rufibach, within MSc biostatistics program at University of Zurich

2009/09-12: Biostatistical methods, Part II: Statistical methods for clinical trials

Kaspar Rufibach, within MSc biostatistics program at University of Zurich

2009/02-05: Likelihood inference

Leonhard Held and Kaspar Rufibach, within MSc biostatistics program at University of Zurich

2008: Netrin-1 and DCC Expression in brain tumors (in German)

Rita Achermann, Semester thesis, Department of Biostatistics, University of Zurich

2005/10-2006/02: Introduction to Statistics

Kaspar Rufibach, within MSc sport science program at University of Bern

2005/04-05: Introduction to R.

Kaspar Rufibach, continuing studies, University of Bern

2005: Visus under physical stress (in German)

Karin Lanz and Marco Weber, Swiss Technical School for Optometrics, Olten, Switzerland

Working groups

I am a member of several cross-industry working groups. Further information on these is provided below.