Talks

2019

rpact - R Package for Adaptive Clinical Trials
Jul 4, 2019 15:00
Multistate models to improve decision-making and effect quantification in clinical trials
Jun 27, 2019 00:00
Estimand framework in Oncology drug development – impact and opportunities
Jun 4, 2019 00:00
Bayesian Predictive Power: Theory, challenges in implementation, and perspectives
May 23, 2019 00:00
External controls in drug development (with Hans Ulrich Burger)
May 10, 2019 00:00
MIRROS: Phase 3 trial with time-to-event endpoint, cure proportion, and futility interim analysis using response
Apr 2, 2019 00:00
Estimand framework in Oncology drug development -- impact and opportunities
Mar 19, 2019 00:00

2018

Assess Common Surrogate Endpoints in Lymphoma using a Multistate Model
Oct 17, 2018 00:00
More efficient treatment effect estimation in pre-specified subgroups displayed in forest plots for time-to-event outcomes
Oct 4, 2018 00:00
Immortal bias - you live longer if you cannot die
Sep 10, 2018 00:00
Overall survival prediction conditional on post-randomization events: multistate models, landmark analyses, and others
Jun 21, 2018 00:00
The Estimand Framework Applied to Time-to-event Endpoints
Mar 28, 2018 00:00
Estimands and the ICH E9 draft addendum
Feb 13, 2018 00:00

2017

Treatment effect measures for time-to-event endpoints - estimands, analysis strategies, and beyond
Nov 24, 2017 00:00
Construction of an Estimand in a Clinical Trial on Progressive Multiple Sclerosis
Oct 4, 2017 00:00
Evolvement of assurance over the lifecycle of several Phase 3 trials in a large oncology clinical development program
Aug 31, 2017 00:00
Joint modelling of progression-free and overall survival
Jul 12, 2017 00:00
Treatment effect measures for time-to-event endpoints - Estimands and beyond
Jun 13, 2017 00:00
Comparison of clinical development plans for a confirmatory trial with subpopulation selection
Mar 13, 2017 00:00

2016

Bayesian Predictive Power: update after a blinded interim analysis and choice of update after a blinded interim analysis and choice of prior
Dec 12, 2016 00:00
Estimands for time to event endpoints
Nov 14, 2016 00:00
Bayesian Predictive Power: update after a blinded interim analysis and choice of prior
Nov 10, 2016 00:00
Estimands for time to event endpoints in oncology and beyond
Sep 12, 2016 00:00
Bayesian Predictive Power: Choice of Prior and some implications
Aug 23, 2016 00:00
Bayesian Predictive Power: Choice of Prior and some Recommendations for its Use as Probability of Success in Drug Development
May 24, 2016 00:00
Time to think about estimands for time-to-event endpoints? A few examples
May 24, 2016 00:00
Event projection: quantify uncertainty and manage expectations of broader teams
Apr 28, 2016 00:00

2015

A Weibull Regression Model for a Time-to-Event Endpoint with an Interval-Censored Covariate and its Application in Assessing Prentice's Criteria for Surrogacy
Nov 20, 2015 00:00
Bayesian Predictive power: the bathtub phenomenon
Oct 27, 2015 00:00
Comparison of clinical development plans for a confirmatory trial with subpopulation selection
Jun 18, 2015 00:00
Evaluation of possible designs for a three-arm clinical trial: Comparing a closed-testing design to potential alternatives
Jun 16, 2015 00:00
Bayesian predictive power: update after a blinded interim and fallacies
Apr 17, 2015 00:00

2014

How good is your biomarker? Comparison of development plans for confirmatory biomarker enrichment
Nov 20, 2014 00:00
How good is your biomarker? Comparison of development plans for confirmatory biomarker enrichment
Nov 11, 2014 00:00
How statistics can contribute to innovative trials
Sep 18, 2014 00:00
Weibull Regression for a Right-Censored Endpoint with a Censored Covariate
Aug 28, 2014 00:00
Update Bayesian predictive power after a blinded interim analysis
Jul 2, 2014 00:00
Update Bayesian predictive power after a blinded interim analysis
Mar 27, 2014 00:00

2013

Update Bayesian Predictive Power after a blinded interim analysis
Oct 23, 2013 00:00

2011

A smooth ROC curve estimator based on log-concave density estimates
Sep 13, 2011 00:00
Selection models with monotone weight functions in meta analysis
Jun 21, 2011 00:00

2010

Ordered Monotone Regression
Aug 3, 2010 00:00
Ordered Monotone Regression
Mar 2, 2010 00:00
Score regression: a new approach to assess calibration of continuous probabilistic predictions
Jan 26, 2010 00:00
Ordered monotone regression
Jan 12, 2010 00:00

2009

Regularized regression models in R
Feb 11, 2009 00:00

2008

On a new approach to regression models with ordinal explanatory variables
Mar 12, 2008 00:00
A general criterion for multiscale inference
Jan 17, 2008 00:00

2007

Nonparametric Estimation of Log-Concave Densities
Dec 8, 2007 00:00
A general criterion for multiscale inference
Sep 28, 2007 00:00
Predicting Alzheimer from proteomic blood markers
Sep 13, 2007 00:00
On a new approach to regression with ordered explanatory variables
Sep 11, 2007 00:00
Max-domain of attraction for log-concave densities and smooth tail index estimation
Jul 31, 2007 00:00

2006

The log-concave density estimator as a smoother
Nov 11, 2006 00:00
Smoothed semi-parametric tail index estimation and max-domain of attraction for log-concave densities
Mar 15, 2006 00:00

2005

Log-concave density estimation
Aug 23, 2005 00:00
Log-concave density estimation
Jul 27, 2005 00:00
Log-concave density estimation and bump hunting
Jul 19, 2005 00:00

2004

Log-concave density estimation and uniform rate of convergence
Mar 26, 2004 00:00

2003

Computing maximum likelihood estimators of log-concave densities
Aug 6, 2003 00:00